Know Your Blood Parameters: Serum Trypsin/ Trypsinogen

1. Parameter Name

   Serum Trypsin / Trypsinogen

   
   

2. Test Type

   Blood

   
   

3. Normal Range

   Trypsinogen: 10–57 ng/mL (lab-specific)

   
   

4. High Levels Indicate

   Acute pancreatitis, pancreatic duct obstruction, or trauma to the pancreas.

   
   

5. Low Levels Indicate

   Chronic pancreatitis, cystic fibrosis, or pancreatic insufficiency.

   
   

6. Why It's Tested

   To evaluate pancreatic enzyme secretion; trypsinogen is a sensitive marker in newborn screening for cystic fibrosis.

   
   

7. Associated Symptoms (if abnormal)

   Abdominal pain, fat malabsorption, steatorrhea, poor weight gain (in children).

   
   

8. What To Do If Abnormal

   Further evaluation with stool fat test, genetic testing (for CF), or imaging.

   
   

9. Common Conditions Related

   Cystic fibrosis, chronic pancreatitis, pancreatic exocrine insufficiency.

   
   

10. Nutrition or Lifestyle Connection

    Enzyme replacement may be needed; ensure fat-soluble vitamin intake (A, D, E, K); avoid alcohol and smoking.

    
    

11. References (APA Format)

    MedlinePlus. (2023). Trypsin and trypsinogen.

    Cystic Fibrosis Foundation. (2022).