Know Your Blood Parameters: Estradiol (E2)

1. Parameter Name

   Estradiol (E2)

   
   

2. Test Type

   Blood

   
   

3. Normal Range

   Women (Follicular phase): 19 – 140 pg/mL

   Women (Mid-cycle peak): 110 – 410 pg/mL

   Women (Luteal phase): 70 – 250 pg/mL

   Men: 10 – 40 pg/mL

   
   

4. High Levels Indicate

   Ovarian tumors, estrogen therapy, pregnancy.

   
   

5. Low Levels Indicate

   Menopause, ovarian failure, hypogonadism.

   
   

6. Why It's Tested

   To assess ovarian function, menstrual irregularities, fertility, and hormone replacement therapy.

   
   

7. Associated Symptoms (if abnormal)

   High: Breast tenderness, menstrual irregularities.

   Low: Hot flashes, irregular periods, infertility.

   
   

8. What To Do If Abnormal

   Correlate with FSH, LH; consult gynecologist or endocrinologist.

   
   

9. Common Conditions Related

   PCOS, menopause, ovarian failure, estrogen-secreting tumors.

   
   

10. Nutrition or Lifestyle Connection

    Maintain healthy body weight; phytoestrogen-rich foods may modulate levels.

    
    

11. References (APA Format)

    Melmed, S. et al. (2016). Williams Textbook of Endocrinology (13th ed.). Elsevier.

    MedlinePlus. (2023). Estradiol Test. https://medlineplus.gov/lab-tests/estradiol/