Know Your Blood Parameter : MPV

1. Parameter Name 

Mean Platelet Volume (MPV)

2. Test Type 

Blood

3. Normal Range 

7.5 – 11.5 fL (may vary slightly by laboratory)

4. High Levels Indicate 

Larger, younger platelets — may suggest increased platelet production due to bleeding, inflammation, or bone marrow disorders. Seen in ITP (immune thrombocytopenic purpura), sepsis, or after splenectomy.

5. Low Levels Indicate 

Smaller platelets — may indicate bone marrow suppression, aplastic anemia, chemotherapy effects, or Wiskott-Aldrich syndrome.

6. Why It's Tested 

To evaluate platelet function and bone marrow activity, particularly in cases of unexplained bleeding or clotting.

7. Associated Symptoms (if abnormal)

• High: Risk of clot formation, headaches, chest pain in rare cases

• Low: Easy bruising, nosebleeds, prolonged bleeding

  
  

8. What To Do If Abnormal 

Repeat test if needed. Correlate with platelet count and clinical signs. Follow up with hematologist if other blood parameters are abnormal.

9. Common Conditions Related 

ITP, myeloproliferative disorders, inflammatory diseases, bone marrow suppression.

10. Nutrition or Lifestyle Connection 

Ensure a balanced diet rich in vitamin B12, folate, and iron to support bone marrow health. Avoid smoking and manage inflammatory conditions.

11. References (APA Format)

• Pagana, K. D., & Pagana, T. J. (2021). Mosby’s diagnostic and laboratory test reference (15th ed.). Elsevier.

• MedlinePlus. (2023). Mean Platelet Volume (MPV). U.S. National Library of Medicine. https://medlineplus.gov/lab-tests/mpv-mean-platelet-volume/

• Chernecky, C. C., & Berger, B. J. (2013). Laboratory Tests and Diagnostic Procedures (6th ed.). Saunders.

• Mayo Clinic. (2022). Complete blood count (CBC). https://www.mayoclinic.org/tests-procedures/complete-blood-count