Know Your Blood Parameter: MCV

1. Parameter Name 

Mean Corpuscular Volume (MCV)

2. Test Type 

Blood

3. Normal Range

• Adults: 80 – 100 femtoliters (fL)

  
  

4. High Levels Indicate 

Macrocytosis - may be caused by vitamin B12 or folate deficiency, liver disease, alcohol use, hypothyroidism, or bone marrow disorders.

5. Low Levels Indicate 

Microcytosis - often related to iron deficiency, thalassemia, or chronic disease.

6. Why It's Tested 

To help classify the type of anemia and guide further diagnostic tests and treatment.

7. Associated Symptoms (if abnormal) 

Fatigue, weakness, pallor, shortness of breath; symptoms depend on the underlying cause of abnormal MCV.

8. What To Do If Abnormal 

Discuss with a doctor. Follow-up tests may include iron studies, vitamin B12, folate, liver function tests, and peripheral smear.

9. Common Conditions Related 

Iron deficiency anemia, vitamin B12 deficiency anemia, folate deficiency, liver disease, thalassemia.

10. Nutrition or Lifestyle Connection 

Maintain a balanced diet rich in iron (leafy greens, legumes), vitamin B12 (dairy, fish, eggs), and folate (citrus fruits, beans). Avoid excessive alcohol intake.

11. References (APA Format)

• MedlinePlus. (2023). Mean corpuscular volume (MCV). U.S. National Library of Medicine. https://medlineplus.gov/lab-tests/mean-corpuscular-volume-mcv/ 

• Pagana, K. D., & Pagana, T. J. (2021). Mosby’s diagnostic and laboratory test reference (15th ed.). Elsevier.

• Mayo Clinic. (2022). Anemia classification and MCV values. https://www.mayoclinic.org/diseases-conditions/anemia

• American Society of Hematology. (2021). Understanding anemia. https://www.hematology.org/education/patients/anemia