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Know Your Blood Parameter: AST (SGOT)

Updated: May 26

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  1. Parameter Name 

    Aspartate Aminotransferase (AST / SGOT)


  2. Test Type 

    Blood


  3. Normal Range

    • Men: 10 – 40 U/L

    • Women: 9 – 32 U/L (May vary slightly by lab)


  4. High Levels Indicate 

    Liver cell injury, but also found in heart and muscle tissues. Elevated in hepatitis, muscle injury, heart attack, or strenuous exercise.


  5. Low Levels Indicate 

    Usually not clinically significant. May be seen in vitamin B6 deficiency.


  6. Why It's Tested 

    Assesses liver and muscle health. Often used alongside ALT to evaluate liver injury.


  7. Associated Symptoms (if abnormal) Symptoms depend on the underlying cause: jaundice, fatigue, muscle pain, or chest pain.


  8. What To Do If Abnormal 

    Compared with ALT levels. Evaluate for liver disease, cardiac issues, or muscle disorders. May need imaging or further testing.


  9. Common Conditions Related 

    Hepatitis, fatty liver disease, cirrhosis, myocardial infarction, muscle injury.


  10. Nutrition or Lifestyle Connection 

    Limit alcohol, avoid hepatotoxic medications, support liver with antioxidants (vitamin E, C), and maintain an active lifestyle.


  11. References (APA Format) 

    MedlinePlus. (2023). Aspartate aminotransferase (AST) test. 

    Mayo Clinic. (2022). Liver function tests. 

    American Association for Clinical Chemistry. (2023). AST test overview.

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